Drug Delivery System for Poorly Water-soluble Anti-tumor Drug SN-38 Utilizing L-PGDS
نویسندگان
چکیده
Masatoshi Nakatsuji, Haruka Inoue, Masaki Kohno, Mayu Saito, Syogo Tsuge, Shota Shimizu, Osamu Ishibashi Osaka Prefecture University, Graduate School of Life and Environmental Sciences 1-1 Gakuen-cho, Nakaku, Sakai, Osaka 599-8531, Japan [email protected]; [email protected]; [email protected]; [email protected]; [email protected]; [email protected]; [email protected]
منابع مشابه
Human Lipocalin-Type Prostaglandin D Synthase-Based Drug Delivery System for Poorly Water-Soluble Anti-Cancer Drug SN-38
Lipocalin-type prostaglandin D synthase (L-PGDS) is a member of the lipocalin superfamily, which is composed of secretory transporter proteins, and binds a wide variety of small hydrophobic molecules. Using this function, we have reported the feasibility of using L-PGDS as a novel drug delivery vehicle for poorly water-soluble drugs. In this study, we show the development of a drug delivery sys...
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تاریخ انتشار 2014